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What is Drysol?

Drysol (aluminum chloride hexahydrate) is a prescribed medication used to treat hyperhidrosis. It is for those who suffer from excessive sweating, known medically as hyperhidrosis.

Prescription and Non-Prescription Strength
Aluminum salts such as aluminum chloride or aluminum chlorohydrate are the most commonly used topical treatments for hyperhidrosis. Over the counter antiperspirants containing aluminum chloride are available in varying concentrations. The maximum is usually 15% – 19%.

The metal complex produces a precipitation in the sweat gland ducts. These block the epidermal sweat duct or promote atrophy and vacuolization of the glandular secretory cells.

Higher concentrated solutions are available up to 25% with a prescription (Drysol, Xerac AC, Certain Dri). Studies with high concentrations have shown good results. In many cases, irritation, and a burning sensation are common side effects.

The patient puts on the solution at bedtime and washes it off 6-8 hours later. In order to get the maximum effect, gloves should be worn while covering the applied area.

Drysol: Long-Term Risks?

We do not know if there is a long-term risk when using aluminum chloride salts. There will be additional consideration for patients with kidney problems. We are aware that over the last several decades more questions have arisen about metallic compounds (prescribed and over the counter) in regards to their long-term safety.

Unfortunately, no known studies with accurate results are available. The disadvantages of these various lotions are the fact that they are used continuously to achieve the maximum results. Patients with severe cases of hyperhidrosis do not have a high ratio of success using these products.

Additional Information:
Learn about other Alternate Hyperhidrosis Treatments